How it works
The wheel rotates about a horizontal axis — lifting culture up and over, with no high-shear tip speed.
BioPure Vertical-Wheel® · 60 mL → 80 L
One wheel. Five scales.
Zero re-engineering.
From a 60 mL discovery flask to an 80 L GMP run — the same gentle geometry, the same CQAs, the same cells.
● Reference geometry
Open hoop · 3 pitched blades · horizontal axle
Continuum of scale
View all systems →One mixing geometry. From bench to commercial.
Scroll the lineup
Every part. Engineered for living cells.
Bench to commercial — one mixing geometry
Exploded view active · 0.1L
The Vertical Wheel advantageLow-shear mixing.
Explore the technology
Low-shear mixing.
Linear scale-up.
Stirred-tank impellers tear delicate cells apart. The Vertical-Wheel® uses a single, gentle mixing geometry that scales identically from 60 mL to 80 L — preserving viability, potency, and CQAs across every transfer.
Shear stress92% lower
Mixing uniformity99%
Cell viability after 7d96%
Linear scale-up factor95%
Vertical Wheel · isometricVW-80 / Ø 220mm
Therapeutic applications
All applications →Engineered for the modalities defining the next decade.
Scientific validation
Open validation hub →Peer-reviewed performance, end to end.
From the lab bench
“We locked the process at 3 L on a Friday.
By Tuesday, the same process was running clean at 80 L.”
JS
Dr. J. Sato
Head of Process Development · Allogeneic MSC program
In partnership with leading research and clinical institutions
MIT
Stanford Med
Karolinska
Memorial Sloan Kettering
Fred Hutch
Mass General
Genentech
Novartis CGT
Lonza
Catalent
ETH Zürich
Imperial College
MIT
Stanford Med
Karolinska
Memorial Sloan Kettering
Fred Hutch
Mass General
Genentech
Novartis CGT
Lonza
Catalent
ETH Zürich
Imperial College
For investors
Investor brief →The picks-and-shovels of the cell therapy decade.
$24B
Cell therapy TAM by 2030
32%
Annual market CAGR
84+
Granted & pending patents
12 / 15
Top-15 pharma in pipeline
BeginThe cells you're growing today
The cells you're growing today
will save someone next year.
Don't let the bioreactor be the reason they don't.